Five years after the first movie, Dr. Yehia marries Lobna and is assigned a new case from the 8-West Women's Ward. Someone is trying to manipulate his life as well as his family's. In an attempt to take control of the ongoing events and solve the mysteries he's facing, Yehia turns to the "Blue Elephant" pills.
A grandfather stole a rare masterpiece belonging to the late singer, Umm Kulthum, in his youth. Years later, he's being chased by those who want it back and he has to go to his only grandson for help.
Asked by his boss to share a woman's personal information, a mobile phone sales rep falls in love with the target whose data he's stealing.